Plasmode’ Simulation (Plasmode)
Creates realistic simulated datasets for causal inference based on a user-supplied example study, Franklin JM, Schneeweiss S, Polinski JM, and Rassen JA (2014) <doi:10.1016/j.csda.2013.10.018>. It samples units from the data with replacement, and then simulates the exposure, the outcome, or both, based on the observed covariate values in the real data.

Read Exported Data from ‘SoftMax Pro’ (softermax)
Read microtiter plate data and templates exported from Molecular Devices ‘SoftMax Pro’ software <https://…/softmax-pro-7-software>. Data exported by ‘SoftMax Pro’ version 5.4 and greater are supported.

Over Time Variable Plots (otvPlots)
Enables automated visualization of variable distribution and changes over time for predictive model building. Computes summary statistics aggregated by time for large datasets, and creates plots for variable level monitoring.

Metaheuristic for Optimization (metaheuristicOpt)
An implementation of metaheuristic algorithms for continuous optimization. Currently, the package contains the implementations of the following algorithms: particle swarm optimization (Kennedy and Eberhart, 1995), ant lion optimizer (Mirjalili, 2015 <doi:10.1016/j.advengsoft.2015.01.010>), grey wolf optimizer (Mirjalili et al., 2014 <doi:10.1016/j.advengsoft.2013.12.007>), dragonfly algorithm (Mirjalili, 2015 <doi:10.1007/s00521-015-1920-1>), firefly algorithm (Yang, 2009 <doi:10.1007/978-3-642-04944-6_14>), genetic algorithm (Holland, 1992, ISBN:978-0262581110), grasshopper optimisation algorithm (Saremi et al., 2017 <doi:10.1016/j.advengsoft.2017.01.004>), harmony search algorithm (Mahdavi et al., 2007 <doi:10.1016/j.amc.2006.11.033>), moth flame optimizer (Mirjalili, 2015 <doi:10.1016/j.knosys.2015.07.006>, sine cosine algorithm (Mirjalili, 2016 <doi:10.1016/j.knosys.2015.12.022>) and whale optimization algorithm (Mirjalili and Lewis, 2016 <doi:10.1016/j.advengsoft.2016.01.008>).

Create Visual Predictive Checks (vpc)
Visual predictive checks are a commonly used diagnostic plot in pharmacometrics, showing how certain statistics (percentiles) for observed data compare to those same statistics for data simulated from a model. The package can generate VPCs for continuous, categorical, censored, and (repeated) time-to-event data.

Quickly View Data Frames in Excel, Build Folder Paths and Create Date Vectors (rmsfuns)
Contains several useful navigation helper functions, including easily building folder paths, quick viewing dataframes in ‘Excel’, creating date vectors and changing the console prompt to reflect time.

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