Nonlinear Mixed Effects Models in Population Pharmacokinetics and Pharmacodynamics (nlmixr)
Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmac …

Quantifying Performance of a Binary Classifier Through Weight of Evidence (wevid)
The distributions of the weight of evidence (log Bayes factor) favouring case over noncase status in a test dataset (or test folds generated by cross-v …

Bayesian Estimation of the Evolutionary Rate Matrix (ratematrix)
Estimates the evolutionary rate matrix (R) using Markov chain Monte Carlo (MCMC) as described in Caetano and Harmon (2017) <doi:10.1111/2041-210X.12 …

Econometric Analysis of Explosive Time Series (exuber)
Testing for and dating periods of explosive dynamics (exuberance) in time series using recursive unit root tests as proposed by Phillips, P. C., Shi, S …

Equi-Rank Hierarchical Clustering Validation (erhcv)
Assesses the statistical significance of clusters for a given dataset through bootstrapping and hypothesis testing of a given matrix of empirical Spear …

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